Fig. 5: Strychnine and glycine within the canonical binding site.
From: Conformational transitions and allosteric modulation in a heteromeric glycine receptor
The binding pocket for A strychnine in αβGlyR-Stry and B glycine in αβGlyR-Gly shown at different angles. Map density is shown at σ = 0.3 and σ = 0.55 for strychnine and glycine, respectively. LigPlot analysis is shown on the right. C Overlaid models show structural rearrangements between αβGlyR-Stry and αβGlyR-Gly. Ligands are omitted for clarity.
