Table 3 Assessment results

From: Characterisation of ASD traits among a cohort of children with isolated fetal ventriculomegaly

Assessments

CN

VM

CN vs VM

VM -ASD

VM + ASD

CN vs VM-ASD

CN vs VM + ASD

 

n = 10

  

n = 24

 

n = 15

 

n = 9

 

(mean ± SD)

(mean ± SD)

(mean ± SD)

(mean ± SD)

ADOS-2 Comparison score

1.2

±

0.4

2.9

±

2.1

p = 0.04

1.7

±

0.7

5.6

±

1.1

NS

p < 0.0001

Preschool language delay n (%)

0

(0%)

9

(39%)

 

3

(20%)

6

(66.6%)

  

Full Scale IQ (WPPSI-IV)

114

±

13

107

±

20

NS

114

±

19

93

±

14

NS

NS

Tracking accuracy (Track-it) (% successful trials)

89%

  

81%

  

p = 0.04

78%

  

87%

  

NS

NS

Working memory (Track-it) (%successful trials)

97%

  

88%

  

p = 0.02

88%

  

88%

  

NS

p = 0.009

Adaptive Skills (Vineland-II)

               

 Adaptive Behaviour

108

±

9

104

±

15

NS

107

±

11

99

±

19

NS

NS

 Daily Living Skills

104

±

8

103

±

14

NS

105

±

10

99

±

18

NS

NS

Behaviour (CBCL)

               

 Total behaviour problems

46.4

±

8.4

44.3

±

12.0

NS

41.3

±

14.6

51.0

±

9.0

NS

NS

 Internalising

46.5

±

9.0

46.7

±

11.0

NS

42.6

±

8.4

55.4

±

10.9

NS

NS

 Externalising

47.1

±

9.5

43.9

±

11.4

NS

41.7

±

9.3

48.4

±

13.9

NS

NS

Sensory processing (SSP-2)

               

 Tactile Sensitivity

32.8

±

1.3

32.0

±

3.8

NS

32.7

±

2.4

30.4

±

5.4

NS

NS

 Taste/Smell Sensitivity

16.7

±

3.9

17.7

±

3.6

NS

17.9

±

3.3

17.4

±

4.1

NS

NS

 Movement sensitivity

14.0

±

1.1

14.5

±

1.1

NS

14.7

±

0.7

14.0

±

1.6

NS

NS

 Under-responsive/Seeks Sensation

29.2

±

2.7

28.1

±

5.3

NS

28.9

±

3.6

26.6

±

7.6

NS

NS

 Auditory filtering

25.4

±

3.2

24.6

±

5.0

NS

26.1

±

3.1

21.7

±

6.6

NS

NS

 Low Energy/weak

29.6

±

0.9

28.2

±

3.0

NS

28.0

±

3.3

28.7

±

2.4

NS

NS

 Visual/Auditory Sensitivity

21.5

±

3.1

22.3

±

3.0

NS

22.7

±

1.9

21.4

±

4.5

NS

NS

Executive function (BRIEF-P)

               

 Global executive composite

49.9

±

6.3

51.2

±

14.4

NS

46.0

±

8.4

61.6

±

17.9

NS

NS

 Inhibit

50.5

±

4.5

49.9

±

12.2

NS

45.7

±

8.3

58.1

±

14.4

NS

NS

 Shift

46.3

±

8.7

49.4

±

10.2

NS

45.6

±

6.5

57.0

±

11.9

NS

NS

 Emotion Control

49.0

±

9.1

54.5

±

14.5

NS

50.4

±

10.7

62.7

±

17.3

NS

NS

 Working memory

50.5

±

6.7

51.6

±

15.1

NS

47.5

±

9.0

59.7

±

20.6

NS

NS

 Plan/Organise

52.5

±

11.2

50.5

±

13.2

NS

46.9

±

9.4

57.9

±

16.4

NS

NS

Movement/Co-ordination (Little DCDQ)

               

 Total score

71.3

±

2.7

70.4

±

6.8

NS

71.5

±

4.5

68.0

±

9.7

NS

NS

  1. CN control cohort, VM Ventriculomegaly cohort, VM-ASD Ventriculomegaly and ADOS-2 non-spectrum classification, VM+ASD Ventriculomegaly and ADOS-2 autism/ASD classification, NS no significance, p > 0.05. Statistical analysis for ADOS-2 Comparison score, BRIEF-P, CBCL, Little DCDQ and SSP-2: Kruskal–Wallis, two-sided, Bonferroni correction applied. Statistical analysis for Full Scale IQ, Track-it and Vineland-III: ANOVA, two-sided, Bonferroni correction applied. P values <0.05 are highlighted in bold.