Fig. 3: hnRNP F is required for IgG1 CSR.
From: The RNA-binding protein hnRNP F is required for the germinal center B cell response
a ELISA of determining antibody titers of total IgM, IgG1, IgG2b, IgG3, and IgA in sera of unimmunized WT (n = 8) and Hnrnpf KO (n = 8) mice. Data are from one single experiment. b, c Flow cytometry measuring CSR to IgG3 or IgG1 in activated B cells with indicated stimulation (n = 7 per group). Data are representative of four independent experiments (b). An unpaired two-tailed student’s t-test was used for the statistical analysis (a and c). Data are presented as mean values ± SD (a and c). Source data are provided as a Source Data file.
