Fig. 2: Overview of mouse sleep fMRI dataset. | Nature Communications

Fig. 2: Overview of mouse sleep fMRI dataset.

From: Sleep fMRI with simultaneous electrophysiology at 9.4 T in male mice

Fig. 2

a Mean power spectrum of raw and denoised ECoG signals for ECoG-fMRI sessions and LFP signals for LFP-fMRI sessions. b Representative denoised LFP and EMG signals during fMRI scanning. Upper panel, broadband (0.5~512 Hz) LFP signal; Lower panel, band-pass filtered (120~250 Hz) LFP signal. Red shadow indicated sharp wave ripple (SWR) events. c Representative example of (temporal) signal-to-noise, i.e., (t)SNR, of our raw fMRI signal. d Small head motion level of ECoG/LFP-fMRI sessions during fMRI scanning (left panel) and minimal head motion effects on BOLD signals after the “6 rp + 6 Δrp + 40 PCs” regression (right panel). Notably, the in-plane spatial resolution of EPI images was 200 μm. The number above each violin plot represented the mean Pearson’s correlation coefficients (C.C.) between frame-wise displacement (FD) and DVARS. e A representative session of mouse sleep fMRI with AW, NREM and REM sleep states (Mouse 26, ch5, 7400s–8400s). From upper to lower panels: power spectrogram of ECoG signal, amplitude of EMG signal, global BOLD signal and voxel-wise whole-brain BOLD signals. AW, awake; NREM, non-rapid eye movement; REM, rapid eye movement. f Averaged (left panel) and time dependent (right panel) probability of each brain state during sleep fMRI scanning (n = 46 sessions from 24 mice). g Overview of mouse sleep fMRI dataset. The number of events here were counted under the sampling rate of 1024 Hz. Cartoon mouse images were drawn by Figdraw. The dataset is openly accessible at https://doi.org/10.12412/BSDC.1668502646.20001. Source data are provided as a Source Data file.

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