Fig. 6: Hippocampal involvement in state transition dynamics and prediction.
From: Sleep fMRI with simultaneous electrophysiology at 9.4 T in male mice
a Differences of power spectrograms between “NREM to AW” (720 epochs) or “NREM to REM” (29 epochs) transition and “NREM only” (2521 epochs) state (two-sample t-test, two tails, p < 0.05). b Representative trace of sharp wave ripples (SWRs) and spindle events. Broadband (raw, 0.5-512 Hz) LFP or iEEG signal together with their band-pass filtered (LFP: 120-250 Hz, iEEG: 10-16 Hz) signals. Purple and brown shadows represented SWRs and spindle events, respectively. c, d Significant decrease of SWRs (c) and spindle (d) probabilities per second prior to state transitions, compared to “NREM only” state (two-sample t-test, left tail, p < 0.05). Colored numbers, the earliest time of significantly lower event probabilities. Color lines (or shadows), mean (+/− SEM.) event probabilities. Source data are provided as a Source Data file.
