Table 2 Clinical observations during hospitalization of non-PASC and PASC patients

From: Post-acute sequelae of COVID-19 is characterized by diminished peripheral CD8+β7 integrin+ T cells and anti-SARS-CoV-2 IgA response

Parameter

Non-PASC (n = 65)

PASC (n = 62)

Statistical analysis*

   

Effect size

p value

Hospital Admission, n (%)

Not hospitalized

12 (18)

12 (19)

0.011

0.898

Hospitalized

53 (82)

50 (81)

  

Worst Disease Stage, n (%)

I

7 (11)

8 (13)

0.055

0.944

IIa

7 (11)

5 (8)

  

IIb

38 (58)

36 (58)

  

III

13 (20)

13 (21)

  

Maximum ventilatory support, n (%)

Mechanical Invasive Ventilation

9 (14)

8 (13)

0.066

0.997

Mechanical Non-invasive Ventilation

4 (6)

4 (7)

  

High-Flow Oxygen

12 (19)

10 (16)

  

Conventional Oxygen (high)

9 (14)

10 (16)

  

Conventional Oxygen (low)

17 (26)

17 (27)

  

Room-air but needing health care

1 (1)

1 (2)

  

Room-air not needing health care

1 (1)

0

  

Not hospitalized

12 (19)

12 (19)

  

Simplified disease severity, n (%)

Mild (Non-hospitalized to conventional oxygen)

40 (62)

40 (65)

0.031

0.728

Severe (High flow Oxygen to mechanical ventilation)

25 (38)

22 (35)

  

Period between (days)

Symptoms and diagnosis

4 (0–14)

5 (0–16)

0.140

0.115

Symptoms and hospitalization

7 (0–14)

9 (0–16)

0.110

0.271

Symptoms and appointment

165 (60–285)

165 (78–281)

0.012

0.341

Length of stay in the Hospital

10 (2–95)

12 (3–60)

0.024

0.551

Laboratory parameters, mean (range)

Ratio PaO2/FiO2 at admission

269.3

(65–371)

274.4

(103–491)

0.129

0.176

Worst Ratio PaO2/FiO2

147.8

(50–5888)

130.1

(46–749)

0.021

0.840

Lowest lymphocyte number during hospitalization

(lymphocytes/µL)

800

(200–1900)

700

(200–3200)

0.073

0.425

Highest C-reactive protein during hospitalization

(mg/dL)

158.4

(9–477)

149.9

(2–393)

0.062

0.496

Highest Ferritin level during hospitalization

(ng/mL)

1752

(8–6866)

1343

(133–12291)

0.153

0.141

Highest D-dimer level during hospitalization

(ng/mL)

1356

(341–4400)

1387

(261–4400)

0.020

0.830

  1. * For categorical variables Chi-square test was used to access the dependence of variables; effect size measures (Phi or Cramer’s V to 2 × 2 comparations or more, respectively) and p-value are reported. For scale variables, Mann-Whitney test was employed; effect size measure (r) and p-value are reported.