Fig. 2: Distribution of CAZymes in the CGR2 genomes.
From: The genomic landscape of reference genomes of cultivated human gut bacteria
a Differences in the numbers of genes encoding GH and PL, and the numbers of GH and PL families represented in these genomes. b Simplified illustration showing the degradation of dietary fibers and the synthesis of SCFAs by the dominant genera (see “Methods”). Ratio of the numbers of strains in top five genera with complete pathways and in genera of CGR2 is shown as pie plot charts (see Supplementary Data 6). Phylum annotation of bar chart as in (a). c Simplified schematics of pathways involved in HMO degradation and phylogenetic tree of 3324 genomes combined with the heatmap on the outermost layer indicating the presence or absence of HMO-degrading GH and CBM genes. The colored rings around the tree represent the taxonomic classifications using the same annotation as in panel (a). LNT, lacto-N-tetrose. LNB, lacto-N-biose. LNBP, lacto-N-biose phosphorylases. LNnT, lacto-N-neotetraose. Star marks bifidobacteria. d PCoA based on Bray–Curtis dissimilarity of the numbers of HMO-degrading CAZyme genes. Ellipses cover 95% of the genomes for each phylum. Phylum annotation as in (a).
