Fig. 4: Differential biological pathways in each monocyte cluster between HAPH patients and controls.

Gene Ontology analysis (biological process) of the DEGs in C0 (a), C1 (b) and C2 (c) monocytes between the HAPH and control samples. d Boxplot showing the mean pathway signature score of each monocyte subset from each group. ***p < 0.001; ****p < 0.0001; using unpaired Wilcox rank sum test. HAPH high-altitude pulmonary hypertension, DEGs differentially expressed genes.