Fig. 3: High coverage and sensitivity of 4D peak detection.
From: A mass spectrum-oriented computational method for ion mobility-resolved untargeted metabolomics
a, b The numbers of 4D peaks with MS2 spectra achieved by different software tools in different biological samples in positive (a) and negative (b) modes (n = 6 technical replicates for each sample type). c, d Overlaps of 4D peaks in human urine samples detected by different software tools in positive (c) and negative (d) modes. e, f The numbers of detected 4D peaks in serially diluted urine samples (10 to 1000 times) in positive (e) and negative (f) modes (n = 6 technical replicates for each dilution sample). g Peak fidelity rates of 4D peaks in biological samples obtained from Met4DX. In a–f, we only counted 4D peaks with MS2 spectra obtained from MS-DIAL and MetaboScape for the comparisons.
