Fig. 1: Extreme case of heterotopic ossification.
From: Enhancer hijacking at the ARHGAP36 locus is associated with connective tissue to bone transformation
a Computed tomography (CT) scan at the age of 5 years shows the muscle-to-bone transformation in the proband. b Array-CGH detected an 820 kb duplication on chr2. c Whole genome sequencing mapped the duplication to the chrX (orange: chrX; blue: chr2). d Sanger sequencing mapped the breakpoints at the base pair level. e Schematic representation of the duplicated genes from chr2 and the insertion at the ARHGAP36/IGSF1 locus in chrX.
