Table 2 Adjusted vaccine effectiveness of inactivated Covid-19 vaccine against Covid-19 outcomes
Unvaccinated (N = 3,317,475) | Vaccinated (N = 3,317,475) | Risk difference per million PWs (95% CI) | VE (95% CI) | |||
|---|---|---|---|---|---|---|
Events | Risk per million PWs | Events | Risk per million PWs | |||
Outcome 1: Documented SARS-CoV-2 infection | ||||||
Overall | 48,447 | 436.1 | 36,581 | 328.8 | 107.3 (106.8, 107.8) | 24.7 (23.7, 25.7) |
Age group—no. | ||||||
60–69 years old | 32,458 | 437.2 | 25,124 | 337.9 | 99.3 (98.7, 99.9) | 22.8 (21.5, 24.0) |
70–79 years old | 13,332 | 423.7 | 9849 | 312.5 | 111.2 (110.2, 112.2) | 26.4 (24.5, 28.3) |
80–89 years old | 2501 | 481.5 | 1532 | 294.2 | 187.3 (183.2, 191.4) | 38.9 (34.9, 42.7) |
90 years old and above | 156 | 794.8 | 76 | 385.3 | 409.6 (371.4, 447.6) | 52.1 (37.0, 63.6) |
Sex—no. (%) | ||||||
Male | 23,800 | 427 | 18,288 | 327.6 | 99.4 (98.7, 100.1) | 23.4 (21.9, 24.9) |
Female | 24,647 | 445.2 | 18,293 | 329.9 | 115.3 (114.5, 116.1) | 25.9 (24.5, 27.4) |
Chronic disease—no. | ||||||
0 | 27,738 | 433.9 | 22,001 | 343.7 | 89.6 (89.0, 90.1) | 20.9 (19.5, 22.3) |
≥1 | 20,709 | 439.1 | 14,580 | 308.5 | 129.4 (128.5, 130.4) | 29.8 (28.2, 31.3) |
Outcome 2: Severe/critical Covid-19 | ||||||
Overall | 601 | 5.4 | 81 | 0.7 | 4.7 (4.4, 5.0) | 86.6 (83.1, 89.4) |
Age group—no. (%) | ||||||
60–69 years old | 250 | 3.4 | 20 | 0.3 | 3.1 (2.8, 3.4) | 91.8 (87.1, 94.8) |
70–79 years old | 201 | 6.4 | 39 | 1.2 | 5.2 (4.7, 5.6) | 80.7 (72.7, 86.3) |
80–89 years old | 135 | 26.0 | 18 | 3.5 | 22.5 (19.7, 25.3) | 86.7 (78.3, 91.9) |
90 years old and above | 15 | 76.4 | 4 | 20.3 | 56.1 (37.3, 74.1) | 73.6 (20.4, 91.2) |
Sex—no. (%) | ||||||
Male | 184 | 3.3 | 24 | 0.4 | 2.9 (2.6, 3.2) | 86.8 (79.8, 91.4) |
Female | 417 | 7.5 | 57 | 1.0 | 6.5 (6.0, 7.0) | 86.5 (82.2, 89.8) |
Chronic disease—no. | ||||||
0 | 269 | 4.2 | 32 | 0.5 | 3.7 (3.4, 4.0) | 88.1 (82.9, 91.8) |
≥1 | 332 | 7.0 | 49 | 1.0 | 6.0 (5.5, 6.5) | 85.4 (80.2, 89.2) |
Outcome 3: Covid-19-related death | ||||||
Overall | 190 | 1.7 | 13 | 0.1 | 1.6 (1.4, 1.8) | 93.2 (88.0, 96.1) |
Age group—no. (%) | ||||||
60–69 years old | 64 | 0.9 | 2 | 0.0 | 1.2 (0.9, 1.4) | 96.8 (87.0, 99.2) |
70–79 years old | 67 | 2.1 | 7 | 0.2 | 2.0 (1.7, 2.3) | 89.5 (77.1, 95.2) |
80–89 years old | 52 | 10.0 | 3 | 0.6 | 1.2 (0.9, 1.4) | 94.2 (81.5, 98.2) |
90 years old and above | 7 | 35.7 | 1 | 5.1 | 2.0 (1.7, 2.3) | 85.8 (−15.5, 98.3) |
Sex—no. | ||||||
Male | 68 | 1.2 | 3 | 0.1 | 1.1 (0.9, 1.3) | 95.6 (86.1, 98.6) |
Female | 122 | 2.2 | 10 | 0.2 | 2.0 (1.7, 2.3) | 91.8 (84.3, 95.7) |
Chronic disease—no. (%) | ||||||
0 | 108 | 1.7 | 3 | 0.0 | 1.6 (1.4, 1.9) | 97.2 (91.3, 99.1) |
≥1 | 82 | 1.7 | 10 | 0.2 | 1.5 (1.3, 1.8) | 87.8 (76.3, 93.7) |
