Fig. 6: In vivo renal oxygenation and vascular image of a mouse kidney in an oxygen-challenging test.
From: Hybrid photoacoustic and fast super-resolution ultrasound imaging

a Directional blood flow map and b blood speed map of a mouse kidney when the mouse inhales 100% oxygen. c An ultrafast plane-wave ultrasound image of a mouse kidney. d–f The dual-contrast images show co-registered PA renal oxygenation image and ULM blood speed image, recorded in d 100%, e 3%, and f 20% of oxygen inhalations. g The zoom-in ULM blood flow speed maps represent the highlighted regions in (b) under various levels of oxygen inhalations. h Quantitative analysis of the blood speed change as a function of time over 150 sec of recording. i Quantitative analysis of the hemoglobin oxygenation changes as a function of time over 150 sec of recording. The red (and blue) curve represents the percent change of oxygenated (and deoxygenated) hemoglobin. The ultrasound image is recorded with a frame rate of 500 Hz and a central frequency of 15 MHz.