Fig. 4: Genome-wide dynamic in DNA methylation during age progressed in Chinese pine. | Nature Communications

Fig. 4: Genome-wide dynamic in DNA methylation during age progressed in Chinese pine.

From: The methylation landscape of giga-genome and the epigenetic timer of age in Chinese pine

Fig. 4: Genome-wide dynamic in DNA methylation during age progressed in Chinese pine.The alternative text for this image may have been generated using AI.

a DNA methylation levels of all reserved DMRs between samples with big age gaps (35 y vs. 2 y, 35 y vs. 5 y, and 14 y vs. 2 y) at 2, 5, 14, and 35 years. These reserved DMRs were those that have excluded DMR parts overlapping with DMRs between two biological replicates within each of the four age groups. b The methylation level changes of reserved overlapped hyper-DMRs in at least two comparisons (35 y vs. 2 y, 35 y vs. 5 y, and 14 y vs. 2 y). c The methylation level changes of reserved overlapped hypo-DMRs in at least two comparisons (2 y vs. 14 y, 5 y vs. 35 y, 2 y vs. 35 y). p values were calculated by Mann–Whitney tests (two-sided test), and different letters indicate a p value <0.01. Source data are provided as a Source Data file.

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