Fig. 4: Associations between CSF-to-blood clearance parameters and biomarker concentrations for the different disease categories. | Nature Communications

Fig. 4: Associations between CSF-to-blood clearance parameters and biomarker concentrations for the different disease categories.

From: Plasma neurodegeneration biomarker concentrations associate with glymphatic and meningeal lymphatic measures in neurological disorders

Fig. 4: Associations between CSF-to-blood clearance parameters and biomarker concentrations for the different disease categories.The alternative text for this image may have been generated using AI.

The associations between CSF-to-blood clearance pharmacokinetic variables and plasma biomarker concentrations are shown as Pearson’s correlations (r) [95% confidence interval] for the CSF disease categories A reference (REF), B idiopathic normal pressure hydrocephalus (iNPH), C communicating hydrocephalus (cHC), D arachnoid cyst (AC), E idiopathic intracranial hypertension (IIH), and F spontaneous intracranial hypotension (SIH). Significance levels of Pearson correlation coefficients: *P < 0.05, **P < 0.01, ***P < 0.001 (values in bold are statistically significant to P < 0.05); red boxes for negative correlations and blue boxes for positive correlations. Source data are provided as Source Data file.

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