Fig. 7: Daytime differences in plasma biomarker concentrations between the iNPH and REF categories.

Biomarker concentrations in longitudinally collected plasma samples were compared between iNPH and reference subjects for A Aβ40 (P = 0.106), B Aβ42 (P = 0.431), or C Aβ42/ Aβ40 ratio (P = 0.835), D T-tau (log10 Tau; P = 0.012), E GFAP (P < 0.001), and F NfL (P < 0.001; regression analysis of average plasma biomarker concentrations). Results presented as mean (red line for iNPH and blue line for REF) with 95% confidence intervals (red shaded area for iNPH and blue shaded area for REF). Source data are provided as Source Data file.