Fig. 3: Cell colocalization metrics.
From: Spatial analysis with SPIAT and spaSim to characterize and simulate tissue microenvironments

a Diagrams of the cell colocalization metrics available in SPIAT. b Simulations of common tumor-immune spatial patterns and the scores generated by each metric. For the MS, NMS, and CIN, we chose 500 as the distance parameter. For the cross K function-related metrics, we chose 0–500 as the range of the radii. Simulations were generated with spaSim. APD average pairwise distance, AMD average minimum distance, CIN cells in the neighborhood, MS mixing score, NMS normalized mixing score, AUC area under the curve, CKI cross K intersection. Source data are provided as a Source Data file.