Fig. 1: Sketch illustrating wetting transitions and observed morphologies of the membrane-condensate system.
From: Wetting and complex remodeling of membranes by biomolecular condensates
Membranes (magenta) in contact with biomolecular condensates (cyan) can undergo two wetting transitions from dewetting (a, f) through partial wetting (b, g-left) to complete wetting (c, g-right) modulated by ionic strength and membrane composition. Complex morphological transformations exhibited by interface ruffling and fingering (d) can be observed when excess membrane area is available, or suppressed when this area is retracted upon tension increase (e). Salinity changes can result in the formation of hollow condensates (f), which can also exhibit partial and complete wetting (g) offering additional means of compartmentation in cells.
