Fig. 5: The expected area under the receiver operating characteristic curve (AUC) of a polygenic risk score (PRS) built based on a GWAS of specified sample sizes for lung adenocarcinoma in never-smoking East Asians.

For “1 million controls”, the x-coordinate represents the number of cases, assuming the study has 1 million controls. For “Equal number of cases and controls”, the x-coordinate represents the numbers of cases, assuming the same number of cases and controls.