Fig. 2: REV-I reduces jejunal but not liver SR-B1. | Nature Communications

Fig. 2: REV-I reduces jejunal but not liver SR-B1.

From: Resveratrol intervention attenuates chylomicron secretion via repressing intestinal FXR-induced expression of scavenger receptor SR-B1

Fig. 2: REV-I reduces jejunal but not liver SR-B1.

a Diagram summarizes metabolic processes involved in intestinal lipid (TG) homeostasis. Average TG intake (b) and daily fecal TG loss (c) of mice individually housed in metabolic cages at the end of the 8th week; n = 6. d Jejunal intracellular TG contents; n = 4. e Heatmap shows the expression of genes involved in intestinal lipid metabolism among the three groups of mice (see statistical analysis results of qRT-PCR in Supplementary Table 4); n = 12. f Jejunal (n = 9) and hepatic (n = 3) SR-B1 levels were assessed by Western blotting. g Representative jejunum SR-B1 immunostaining images (brown), along with its quantitative scores at the apical membrane. The scale bar is 300 μm; n = 3. h Representative jejunum SR-B1 immunofluorescence staining images (red), along with its quantitative scores at the apical membrane. The scale bar is 500 μm; n = 3. Statistical significance was evaluated by two-sided one-way ANOVA with Dunnett’s post hoc test (compared with HFD group). *p < 0.05, **p < 0.01, ***p < 0.001. Data are presented as mean ± SD. Source data are provided as a Source Data file.

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