Fig. 1: Spatially resolved multi-omics reveals intratumor heterogeneity of gastric cancer. | Nature Communications

Fig. 1: Spatially resolved multi-omics reveals intratumor heterogeneity of gastric cancer.

From: Spatially resolved multi-omics highlights cell-specific metabolic remodeling and interactions in gastric cancer

Fig. 1

a Strategy of integrated spatially resolved multi-omics for highlighting tumor metabolic remodeling and interactions. b H&E stain image of gastric cancer tissue section from patient “No.0429” and ×40 magnified H&E stain image of different gastric cancer tissue regions, scale bar = 2 mm for whole tissue section, scale bar = 100 μm for magnified images. The experiment was repeated three times. c Metabolite and lipid-driven tissue section segmentation based on the MALDI-MSI data. d Metabolite and lipid-driven in situ PLSA analysis. e Visium array spots colored by graph-based clustering algorithm.

Back to article page