Fig. 6: Mapping of the global motions of the NER-TFIIH complex onto the dCNA communities shows that translocation dynamics is enabled for XPD and suppressed for XPB during lesion scanning. | Nature Communications

Fig. 6: Mapping of the global motions of the NER-TFIIH complex onto the dCNA communities shows that translocation dynamics is enabled for XPD and suppressed for XPB during lesion scanning.

From: Dynamic conformational switching underlies TFIIH function in transcription and DNA repair and impacts genetic diseases

Fig. 6: Mapping of the global motions of the NER-TFIIH complex onto the dCNA communities shows that translocation dynamics is enabled for XPD and suppressed for XPB during lesion scanning.The alternative text for this image may have been generated using AI.

a The first principal mode from PCA analysis of the NER-TFIIH complex; gray arrows indicate the directionality of the motions of the Cα atoms of the assembly; b Zoomed view showing the motion of the XPB communities; c Zoomed view showing the motion of XPD communities. Communities are colored the same as in Fig. 4.

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