Fig. 2: Characterization of NKCOFs.

a Chemical structures of the COFs. b FT-IR spectra of NKCOF-12 and corresponding monomers: TFB (purple), TMT (blue), NKCOF-12 (red). c PXRD patterns of NKCOF-12: measured patterns (red), simulated pattern (black). d Nitrogen adsorption and desorption isotherms of NKCOF-12. The inset shows the pore size distribution profile of NKCOF-12. e SEM image of NKCOF-12 (scale bar = 300 μm, inset: magnified field of view, scale bar = 10 μm). This experiment was independently repeated three times. f Histogram of particle size distribution calculated from SEM image. g PXRD patterns of NKCOF-12 after treatment with simulated gastric fluid (SGF) and simulated intestinal fluid (SIF).