Fig. 4: Computational modeling of chromatin segments with kilobase-scale compartments.
From: Chromatin alternates between A and B compartments at kilobase scale for subgenic organization
a–c Examples of simulated chromatin segments for chr7: 39.5–42.5 Mb, chr7: 95.4–96.5 Mb and chr9: 107.5–110.5 Mb. Each segment is shown with the experimental Hi-C map (left) and a representation of the structures (middle) that were used to build the simulated distance map (right) at 1 kb resolution. The circle and line indicate compartmental features near the diagonal captured by the simulation. d, e Examples modeling genes with discordant compartments are shown for TMEM38B in chromosome 9 and SEM1 in chromosome 7.
