Fig. 2: Longitudinal analysis of xenograft length after life-sustaining kidney xenotransplantation shows minimal growth. | Nature Communications

Fig. 2: Longitudinal analysis of xenograft length after life-sustaining kidney xenotransplantation shows minimal growth.

From: Clinical and molecular correlation defines activity of physiological pathways in life-sustaining kidney xenotransplantation

Fig. 2

a Example ultrasound (US) of NHP M2420 xenograft at 124 days PTT. b Individual animals’ absolute changes in kidney graft length over time. Black solid line is the LOESS estimate, a non-parametric regression method estimating the relationship between absolute length and PTT across all transplants; gray shaded region is 95% confidence interval for the estimate. c As in (b) but for relative change in length over time. Dashed lines represent estimated between US variation based on ultrasounds performed on the same animal in the same week. n = 17 biologically independent transplants for panels b, c. LOESS locally estimated scatterplot smoothing.

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