Table 1 Dissociation constants (Kd) and confidence values (Kd ± confidence values) of ADMA binding to DDAH1-GST, DDAH2-GST, and GST with statistical parameters of result’s significance (amplitude, signal to noise ratio (S/N))

From: A multicentric consortium study demonstrates that dimethylarginine dimethylaminohydrolase 2 is not a dimethylarginine dimethylaminohydrolase

Binding experiment

Amplitude (threshold value)

S/N (threshold value)

Binding status Kd (μM) ± confidence values

ADMA/DDAH1-GST

11.7 (8.4)

30.9 (5)

Stable binding 4.27 ± 0.46

ADMA/DDAH2-GST

5.2 (10.5)

10.6 (5)

n.s Amplitude < threshold

ADMA/GST

0.2 (2.7)

0.5 (5)

n.s Amplitude < threshold

  1. n.s. non-significant.
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