Fig. 3: Distinct engagement of lOFC and S1 after reversals and during re-learning, respectively.
From: Human orbitofrontal cortex signals decision outcomes to sensory cortex during behavioral adaptations
a Significantly enhanced BOLD signals in lOFC immediately after the reversal (RN > LE, one-sided t-test, p = 0.035, family-wise error (FWE) peak-level corrected for multiple comparisons using small-volume correction (SVC)). b Significantly enhanced BOLD signals in bilateral S1 during re-learning after the reversal (RE > LE, one-sided t-test, left S1: p = 0.002, right S1: p = 0.005. FWE peak-level corrected for multiple comparisons using SVC). The activations (p < 0.001, uncorrected, for display purposes only) were superimposed on sagittal, coronal, and axial slices of a standard T1-weighted image from the Colin27 brain template implemented in MRIcron. Chris Rorden’s MRIcron, all rights reserved. Coordinates next to each slice indicate their location in MNI space. Red-yellow coding indicates the t-scores of activation intensities. c The BOLD signals relative to baseline in lOFC and S1 across the four learning phases (LN, LE, RN, RE). The y-axis indicates the z-score of the mean beta value from lOFC and S1 as derived from the general linear model. The error bars indicate the SEM (n = 32 participants). Source data are provided as a Source Data file.
