Fig. 8: Low PDZK1 expression in human gastric and prostate cancers correlates with increased LEF1 activity. | Nature Communications

Fig. 8: Low PDZK1 expression in human gastric and prostate cancers correlates with increased LEF1 activity.

From: Hyperphosphorylated PTEN exerts oncogenic properties

Fig. 8

a Heat map (Row Z-Score) of the 100 top differentially expressed LEF1 target genes with FDR < 0.05 in TGCA-STAD gastric cancers with low PDZK1 expression (bottom 15%; n = 57 cases) versus high PDZK1 expression (top 15%; n = 57 cases). b As in (a) but now for TGCA-PRAD prostate cancers with n = 75 cases in the bottom 15% and n = 75 cases in the top 15% of PDZK1 expression.

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