Fig. 4: The scope of allylation reagents. | Nature Communications

Fig. 4: The scope of allylation reagents.

From: Ketone α-alkylation at the more-hindered site

Fig. 4

Reaction conditions: Ni(COD)2 (10 mol%), L6 (11 mol%), EtOH (0.5 mL), ketone 1h (0.1 mmol), allylic alcohol 5 (0.1 mmol), 80 °C, 12 h. Isolated yields are given. r.r. > 99:1 unless noted. aUsing a 1:1 mixture of Z- and E-3-phenylprop-2-en-1-ol. bThe yield was measured by GC analysis; r.r. = 97:3.

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