Fig. 1: Intrahost emergence of an Omicron BA.1.23 subvariant.
From: Sequential intrahost evolution and onward transmission of SARS-CoV-2 variants

Multiple sequence alignment of the SARS-CoV-2 spike gene indicating the appearance of single nucleotide variants (SNVs) in the consensus sequence of the spike gene in sequential specimens obtained from the index case (Patient 1, P1). Novel SNVs relative to the ancestral BA.1 strain are shown in red and labeled at the bottom of the figure. Bold labels denote signature mutations observed in multiple specimens. Consensus changes in BA.1 compared to the Wuhan-1 strain are shown in blue.