Table. 1 MCSA and ADRC participant and scan characteristics at the most recent visit
CU (N = 1817) | MCI (N = 303) | AlzCS Dem (N = 286) | Total (N = 2406) | |
|---|---|---|---|---|
Age, years | 73 (11) | 80 (9) | 73 (10) | 74 (11) |
Female sex | 881 (48%) | 132 (44%) | 148 (52%) | 1161 (48%) |
Education, years | 15 (3) | 14 (3) | 16 (3) | 15 (3) |
APOE ε4 genotypea | ||||
Non-carrier | 1268 (70%) | 182 (60%) | 76 (27%) | 1526 (63%) |
Carrier | 457 (25%) | 111 (37%) | 172 (60%) | 740 (31%) |
Study | ||||
ADRC | 0 (0%) | 0 (0%) | 257 (90%) | 257 (11%) |
MCSA | 1817 (100%) | 303 (100%) | 29 (10%) | 2149 (89%) |
No. total amyloid-PETs | ||||
1 | 901 (50%) | 150 (50%) | 128 (45%) | 1179 (49%) |
2 | 453 (25%) | 61 (20%) | 71 (25%) | 585 (24%) |
3+ | 463 (25%) | 92 (30%) | 87 (30%) | 642 (27%) |
No. total tau-PETs | ||||
0 | 727 (40%) | 149 (49%) | 90 (31%) | 966 (40%) |
1 | 683 (38%) | 77 (25%) | 107 (37%) | 867 (36%) |
2 | 304 (17%) | 37 (12%) | 39 (14%) | 380 (16%) |
3+ | 103 (6%) | 40 (13%) | 50 (17%) | 193 (8%) |
No. total FLAIR-MRIs | ||||
0 | 8 (0%) | 2 (1%) | 13 (5%) | 23 (1%) |
1 | 732 (40%) | 112 (37%) | 90 (31%) | 934 (39%) |
2 | 495 (27%) | 78 (26%) | 64 (22%) | 637 (26%) |
3+ | 582 (32%) | 111 (37%) | 119 (42%) | 812 (34%) |
No. total DTI-MRIs | ||||
0 | 222 (12%) | 46 (15%) | 132 (46%) | 400 (17%) |
1 | 754 (41%) | 117 (39%) | 92 (32%) | 963 (40%) |
2 | 502 (28%) | 70 (23%) | 37 (13%) | 609 (25%) |
3+ | 339 (19%) | 70 (23%) | 25 (9%) | 434 (18%) |
Amyloid-PET, SUVR | 1.55 (0.36) | 1.93 (0.58) | 2.43 (0.46) | 1.70 (0.50) |
Tau-PET, SUVR | 1.20 (0.10) | 1.29 (0.21) | 1.98 (0.54) | 1.31 (0.35) |
WMH % | 0.88 (0.97) | 1.50 (1.17) | 1.38 (1.28) | 1.01 (1.06) |
FA GCC | 0.62 (0.03) | 0.60 (0.03) | 0.59 (0.03) | 0.61 (0.03) |
