Table. 2 Covariate effects for the primary model fit in the MCSA + ADRC

From: Evidence against a temporal association between cerebrovascular disease and Alzheimer’s disease imaging biomarkers

 

Amyloid PET

Tau PET

WMH%

FA GCC

APOE ε4 carrier

9.0 (7.8, 10.2)

6.1 (3.9, 8.3)

−0.9 (−2.0, 0.2)

−0.5 (−2.1, 1.2)

Female sex

2.1 (1.1, 3.1)

2.6 (0.8, 4.5)

2.3 (1.4, 3.3)

4.1 (2.7, 5.6)

Education 1-yr

0.2 (0.0, 0.4)

0.8 (0.4, 1.1)

−0.1 (−0.3, 0.1)

−0.1 (−0.4, 0.1)

Referral to ADRC

19.0 (18.0, 20.0)

29.4 (27.1, 31.8)

10.4 (9.3, 11.4)

13.3 (11.2, 15.4)

  1. Values shown are mean (95% credible interval). Estimates are in years and represent estimated adjustment or years by which that biomarkers progression is shifted earlier (positive) or later (negative) with vs without that covariate.