Table 1 Training GWAS used as references for PRS construction

From: Evaluating the use of blood pressure polygenic risk scores across race/ethnic background groups

GWAS name

Reference

Trait and sample size

Population

Overlap with TOPMed

MVP

PMID: 305784186

SBP n = 318,492

DBP n = 318,891

Multi-ethnic (69.1% non-Hispanic White, 18.8% non-Hispanic Black, 6.7% Hispanic, 0.77% non-Hispanic Asian and 0.85% non-Hispanic Native American

None

BBJ

PMID:2940301057

SBP n = 136,597

DBP n = 136,615

Japanese

None

UKBB + ICBP

PMID:302246537

SBP n = 757,601

DBP n = 757,601

European and European American

13,516

COGENT

PMID: 284988549

SBP n = 31,155

DBP n = 31,155

African and African American

9708

  1. UKBB + ICBP United Kingdom biobank and the International Consortium of Blood Pressure, MVP Million Veteran Program, BBJ Biobank Japan, COGENT Continental Origins and Genetic Epidemiology Network.