Fig. 3: The overall structure of VibO.
From: A flavin-monooxygenase catalyzing oxepinone formation and the complete biosynthesis of vibralactone
a A schematic diagram showing the domain organization of VibO. b The ribbon-stick representation showing the overall structure of the dimeric VibO. The FAD-binding domain, the middle domain, and the C-terminal domain of VibO are shown in blue/slate, magentas/pink, and cyan/pale cyan, respectively. The two bound cofactor FAD molecules are shown in the stick mode. c The ribbon-stick representation showing the overall architecture of the monomeric VibO with the cofactor FAD. The ribbon diagram representation uses the same color scheme as that in b. d The combined surface charge potential representation (contoured at ±5 kT/eV; blue/red) and the stick-ball model showing the solvent-exposed and highly positive-charged FAD-binding site of VibO. e The combined surface representation and the stick model showing the location of the FAD-binding site in the VibO structure.
