Fig. 3: Comparison of AxqNOR, PacNOR, and Ps cbb3 cox calcium-binding sites. | Nature Communications

Fig. 3: Comparison of AxqNOR, PacNOR, and Ps cbb3 cox calcium-binding sites.

From: A 2.2 Å cryoEM structure of a quinol-dependent NO Reductase shows close similarity to respiratory oxidases

Fig. 3

a The PacNOR Ca binding site is located on the interface between the CytC domain (purple) and the cNOR domain (red). Residues proposed to be involved in the electron transfer from heme c to heme b and heme bh are shown as sticks (PDB ID 3O0R). Water molecules are shown as red spheres, Fe atoms are shown as orange spheres, and calcium ions as green spheres. Hydrogen bonds are shown as black dashed lines and Ca and Fe coordination bonds are shown in green/red dotted lines, respectively. This scheme is used in the figure. b Ps cbb3 cox Ca binding site (PDB: 5DJQ), Ca ion with hemisphere coordination is responsible for non-covalent fixation of ring D carboxylates of heme b and heme b3 from subunit N (pink) it also has a role of supporting subunit O (salmon) linker via Ser102-OD and Glu122-OE2. Cu atom is shown as a dark blue sphere, O2 molecule, bound between heme b3 Fe and CuB is shown as a red stick. c AxqNOR Ca binding site, with protein shown as green ribbons and key residues highlighted as sticks.

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