Fig. 3: Comparison of glycosylation at the proteome, HLA I, and HLA II peptidome levels. | Nature Communications

Fig. 3: Comparison of glycosylation at the proteome, HLA I, and HLA II peptidome levels.

From: Unraveling the glycosylated immunopeptidome with HLA-Glyco

Fig. 3: Comparison of glycosylation at the proteome, HLA I, and HLA II peptidome levels.

a Levels of oxonium ions for HLA classes I and II in three datasets (A: Bassani-Sternberg et al.31, B: Chong et al.34, C: Marcu et al.32), along with the whole proteome in dataset D: Forlani et al.37. b Percentage of Glycosylated PSMs for the HLA class I and II immunopeptidome in 3 datasets (A, B, C), along with the whole proteome in dataset D. c Average glycan mass in Dalton (Da) for the HLA class II immunopeptidome versus the whole proteome in dataset D. d Glycan types for the class II immunopeptidome versus whole proteome in dataset D. e Glycan types found in the low-density lipoprotein receptor-related protein 1 (LRP1) for the class II immunopeptidome versus the whole proteome in dataset D. f Comparison of glycoproteins (top) and glycosites (bottom) found in the HLA class I, II immunopeptidome, and whole proteome of dataset D.

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