Fig. 4: PPP2R1A colocalizes with branched actin in the width of the lamellipodium and colocalizes with NHSL1 at the lamellipodium edge. | Nature Communications

Fig. 4: PPP2R1A colocalizes with branched actin in the width of the lamellipodium and colocalizes with NHSL1 at the lamellipodium edge.

From: PPP2R1A regulates migration persistence through the NHSL1-containing WAVE Shell Complex

Fig. 4: PPP2R1A colocalizes with branched actin in the width of the lamellipodium and colocalizes with NHSL1 at the lamellipodium edge.The alt text for this image may have been generated using AI.

a B16-F1 cells were transiently transfected with mScarlet-PPP2R1A and GFP-NHSL1. A kymograph was drawn along the line shown on the merge. b Overlap of PPP2R1A and NHSL1 over multiple radial line scans registered to the cell edge. Data are shown as mean ± SD, n = 13 line scans. c B16-F1 cells were transiently transfected with mScarlet-PPP2R1A and the Arp2/3 subunit GFP-ARPC1B. A kymograph was drawn along the line shown on the merge. d Overlap of PPP2R1A and ARPC1B over multiple radial line scans registered to the cell edge. Data are shown as mean ± SD, n = 15 line scans. Source data are provided as a Source Data file.

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