Fig. 6: Ultrasensitive electrochemical immunosensor. | Nature Communications

Fig. 6: Ultrasensitive electrochemical immunosensor.

From: Green synthesis of stable hybrid biocatalyst using a hydrogen-bonded, π-π-stacking supramolecular assembly for electrochemical immunosensor

Fig. 6: Ultrasensitive electrochemical immunosensor.The alt text for this image may have been generated using AI.

a Schematic preparation of Ab2/Au NPs/HRP@HOF−100 electrochemical beacon. The pyrene core, formic acid arm and HRP in HRP@HOF-100 structure are shown as dark green prismatic square, purple ball and yellow surface model, respectively. b The principle of the electrochemical immunosensor based on cyclic biocascade for MUC1 detection. c DPV response profile of the developed electrochemical immunosensor as a function of MUC1: 0 (curve a), 1 pg/mL (curve b), 10 pg/mL (curve c), 100 pg/mL (curve d), 1 ng/mL (curve e), 10 ng/mL (curve f) and 100 ng/mL (curve g). d The obtained linear regression equation between the currents and the logarithm of different MUC1 concentrations. e Selectivity of the electrochemical immunosensor toward diverse samples: blank, MB (100 ng/mL), GOx (100 ng/mL), cholesterol (100 ng/mL), MUC1 (100 pg/mL) and a mixture solution (100 pg/mL MUC1, 100 ng/mL MB, 100 ng/mL GOx and 100 ng/mL cholesterol). The data of three independent experiments and calculated error bars (SD) are presented in d, e, SD standard deviation (n = 3). Data are presented as mean values +/−SD.

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