Fig. 1: AAV11 for efficient retrograde access to projection neurons. | Nature Communications

Fig. 1: AAV11 for efficient retrograde access to projection neurons.

From: AAV11 enables efficient retrograde targeting of projection neurons and enhances astrocyte-directed transduction

Fig. 1: AAV11 for efficient retrograde access to projection neurons.

a Schematic diagram of virus injection. AAV11 (3 × 109 vector genomes (VG)) was injected into caudate-putamen (CPu) area of C57BL/6 mice. n = 3. Diagram was created with BioRender.com. b The fluorescence distribution of EGFP at the injection site of CPu. Scale bar = 1 mm. c The spread of the virus to the anterior side. Scale bar = 500 μm. d Neurons were labeled in somatomotor areas (MO). Scale bar = 100 μm. e The spread of the virus to the posterior side, Scale bar = 1 mm. f Neurons were labeled in primary somatosensory area (SSp) and mediodorsal nucleus of thalamus (MD). Scale bar = 100 μm.

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