Table 1 Young’s modulus of PGD raw material, FEA simulated PGD scaffolds, and actual PGD scaffolds made by varying MRH/C and cure time

From: Innovative design of minimal invasive biodegradable poly(glycerol-dodecanoate) nucleus pulposus scaffold with function regeneration

Ttrans (°C)

 

Young’s Modulus at ~37 °C (MPa)

Cure Time (h)

PGD

Simulated Scaffold (FEA)

Actual Scaffold (Experiment)

MRH/C

MRH/C

MRH/C

0.75

1.00

1.50

2.00

0.75

1.00

1.50

2.00

1.50

~28

Long (48-216 h)

2.11 ± 0.42

2.44 ± 0.29

3.13 ± 0.34

2.25 ± 0.11

2.34

2.71

3.48

2.49

Fragile

~32

Med (24-168 h)

1.29 ± 0.27

1.24 ± 0.20

2.43 ± 0.13

1.08 ± 0.08

1.38

1.36

2.70

1.17

2.49 ± 0.23

~36

Short (24-120 h)

N/A

Uncured

1.10 ± 0.20

0.47 ± 0.32

Uncured

Uncured

1.19

0.48

1.23 ± 0.11