Fig. 4: Donor scope with different acceptors. | Nature Communications

Fig. 4: Donor scope with different acceptors.

From: Efficient and versatile formation of glycosidic bonds via catalytic strain-release glycosylation with glycosyl ortho−2,2-dimethoxycarbonylcyclopropylbenzoate donors

Fig. 4

Glycosyl CCBzs derived from different monosaccharide- or oligosaccharide-based hemiacetals are competent coupling partners for strain-release glycosylation. Unless otherwise noted, all reported yields are isolated and purified products. For glycosylation reactions of Nu1 and Nu2, 1.2 equiv of donor and 1.0 equiv of acceptor were used; for glycosylation reactions of Nu3, 1.0 equiv of donor and 1.5 equiv of acceptor were used. rt, room temperature; Nu, nucleophile; Bz, benzoyl; Ac, acetyl; Ph, phenyl; PhthN, phthalimido.

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