Table 4 Detailed statistics for Fig. 4
From: Amphetamine disrupts dopamine axon growth in adolescence by a sex-specific mechanism in mice
Statistical test | Factor | n | Statistic | 95% confidence interval | p value (adjusted where appropriate) | Corresponding figure | |
|---|---|---|---|---|---|---|---|
A | AMPH = 4 Saline = 5 | Fig. 4c | |||||
Two-way mixed ANOVA | Interaction | F (2, 14) = 5.505 | 0.017 | ||||
Subregion (within subject) | F (2, 14) = 11.84 | 0.001 | |||||
Treatment (between subjects) | F (1, 7) = 21.89 | 0.0023 | |||||
Sidak’s multiple comparisons test | Saline vs. AMPH within Cg1 | t(21) = 1.037 | −24.83 to 10.65 | ns | |||
Sidak’s multiple comparisons test | Saline vs. AMPH within PrL | t(21) = 3.998 | −45.08 to −9.605 | <0.01 | |||
Sidak’s multiple comparisons test | Saline vs. AMPH within IL | t(21) = 4.915 | −51.35 to −15.88 | <0.001 | |||
B | AMPH = 4 Saline = 5 | Fig. 4d | |||||
Two-tailed unpaired t test | treatment (unpaired) | t(7) = 2.45 | −7.612 to −0.1352 | 0.0441 | |||
C | AMPH = 4 Saline = 5 | Fig. 4e | |||||
Pearson r | r = −0.7634, r2 = 0.5828 | −0.9473 to −0.2015 | 0.0167 | ||||
D | AMPH = 4 Saline = 5 | Fig. 4f | |||||
Two-tailed unpaired t test | treatment (unpaired) | t(8) = 1.115 | −23.6 to 8.219 | 0.2974 | |||
E | 4 mg/kgAMPH = 6 0.5 mg/kg AMPH = 6 Saline = 6 | Fig. 4g | |||||
One way ANOVA | Dose | F (2, 15) = 17.68 | 0.0001 | ||||
Tukey’s multiple comparisons test | Saline vs. 0.5 | q(15) = 3.107 | −0.1387 to 0.01158 | 0.1041 | |||
Tukey’s multiple comparisons test | Saline vs. 4.0 | q(15) = 8.321 | −0.2454 to −0.0951 | <0.0001 | |||
Tukey’s multiple comparisons test | 0.5 vs. 4.0 | q(15) = 5.214 | −0.1818 to −0.03152 | 0.0059 | |||
F | AMPH = 6 Saline = 4 | Fig. 4j | |||||
Two-way mixed ANOVA | Interaction | F (2, 16) = 0.2576 | 0.7761 | ||||
Subregion (within subject) | F (2, 16) = 11.41 | 0.0008 | |||||
Treatment (between subjects) | F (1, 8) = 0.004941 | 0.9457 | |||||
G | AMPH = 6 Saline = 4 | Fig. 4k | |||||
Two-tailed unpaired t test | treatment (unpaired) | t(8) = 0.5276 | −2.205 to 3.513 | 0.306 |
