Fig. 3: Substrate scope for maleimidation of dipeptides and complex peptides.
From: Modular synthesis of clickable peptides via late-stage maleimidation on C(7)-H tryptophan
Reaction conditions: 4 (0.2 mmol), 2a (0.6 mmol), [RhCp*Cl2]2 (5 mol%), AgNTf2 (20 mol%), Ag2O (1.5 eq), DCM (1.5-2 mL), 80 °C, 12 h.
