Fig. 3: DNA methyltransferases are remarkably diverse and abundant in the accessory genomes of BFG species.

Host species are represented across the top row as squares (area proportional to number of genomes analyzed). DNA methyltransferase gene families (80% AAI, 80% AF) are represented in rectangular grids below as filled circles (with area proportional to number of genes in the family) with colors indicated in the key. Edges connect species with DNA methyltransferase gene families that are encoded by one or more genomes within the species. Location of the given methyltransferase gene family in the core, shell or cloud genome in is indicated by edge color, and edge thickness indicates the number of times the gene family is encoded in the genome of the species. In this analysis, ‘Core’ was defined as presence in >90% of genomes in a species, ‘Shell’ was defined as presence in >10% and ≤90% genomes in a species, and ‘Cloud’ was defined as presence in <10% of genomes in a species.