Table 1 BMI distribution of the investigated subgroups in five patient cohorts

From: Obesity-associated changes in molecular biology of primary breast cancer

  

Total number of patients

Median (range)

Lean (%)

Overweight (%)

Obese (%)

METABRIC

NST ER+/HER2−

215

26.17

(18.55, 46.41)

86 (40.0)

73 (34.0)

56 (26.0)

NST ER−/HER2−

68

25.78

(20.47, 43.46)

30 (44.1)

24 (35.3)

14 (20.6)

ICGC

NST ER+/HER2−

177

26.00

(18.70, 51.80)

67 (37.9)

64 (36.2)

46 (26.0)

NST ER−/HER2−

84

26.00

(18.60, 55.40)

36 (42.9)

30 (35.7)

18 (21.4)

ELBC

ILC ER+/HER2−

545

23.34

(18.51, 40.86)

351 (64.4)

143 (25.2)

51 (9.4)

MINDACT

NST ER+/HER2−

735

25.24

(18.59, 68.68)

354 (48.2)

250 (34.0)

131 (17.8)

NST ER−/HER2−

118

25.28

(19.00, 39.88)

53 (44.9)

54 (45.8)

11 (9.3)

ILC ER+/HER2−

104

24.19

(19.27, 37.05)

65 (62.5)

32 (30.8)

7 (6.7)

Biokey

NST ER+/HER2−

13

24.79

(19.72, 44.08)

6 (46.2)

3 (23.1)

4 (30.8)

NST ER−/HER2−

12

24.13

(22.6, 32.05)

8 (66.7)

2 (16.7)

2 (16.7)

  1. Subgroups were determined by histological subtype, and the ER and HER2 status. Only cases with available molecular profiling data, either genomic profiling, bulk, or single-cell transcriptomic profiling, were included.