Table 1 Characteristics of pancreatic cancer cases and matched controls at the time of prediagnosis CT imaging

Characteristic^a	Cases (N = 714)	Controls (N = 1748)	P value
Age, years^b	67.1 (10.2)	66.8 (10.3)	0.49
Year of CT scan^b			0.39
2003–2010	314 (44)	736 (42)
2011–2017	400 (56)	1012 (58)
Intravenous contrast with CT imaging^b	563 (79)	1409 (81)	0.32
Female^b	340 (48)	827 (47)	0.89
Race^b			0.63
White	659 (92)	1603 (92)
Black	55 (8)	145 (8)
Study site^b			0.53
DFCI/MGB	228 (32)	581 (33)
KPNC	486 (68)	1167 (67)
Body mass index, kg/m^2c	29.3 (6.1)	28.9 (6.5)	0.11
Diabetes	193 (27)	368 (21)	0.001
Cigarette Smoking			<0.0001
Never	276 (39)	772 (44)
Past	242 (34)	674 (39)
Current	119 (17)	199 (11)
Unknown	77 (11)	103 (6)
History of alcohol use			0.44
No/Unknown	638 (89)	1591 (91)
Yes	76 (11)	157 (9)
Prior personal history of cancer	109 (15)	177 (10)	0.0003
Time from prior cancer to prediagnosis scan, years	12.7 (7.8)	11.0 (6.6)	0.06
Indication for CT imaging
Symptoms/suspected conditions of the GI system	108 (15)	189 (11)	0.003
Symptoms/suspected conditions unrelated to the GI system	164 (23)	548 (31)	<0.0001
Systemic symptoms	65 (9)	160 (9)	0.97
New-onset diabetes	4 (1)	6 (0.3)	0.44
Pain	365 (51)	922 (53)	0.46
Other/unknown	190 (27)	361 (21)	0.001
Age at pancreatic cancer diagnosis, years	69.4 (10.3)	NA	NA
Pancreatic cancer diagnosis period			NA
2004–2008	108 (15)	NA
2009–2013	281 (39)	NA
2014–2018	325 (46)	NA
Pancreatic cancer stage at diagnosis			NA
Non-metastatic	370 (52)
Metastatic	326 (46)	NA
Unknown	18 (3)	NA
Mean time from prediagnosis CT imaging to pathological diagnosis, months	22.7 (17.2)	NA	NA
Mean time from at-diagnosis CT imaging to pathological diagnosis, days^d	10 (14)	NA	NA

P values were calculated using chi-square tests for categorical, and two-sided Wilcoxon rank-sum test for continuous variables.
CT computed tomography, DFCI/MGB Dana–Farber Cancer Institute/Mass General Brigham, GI gastrointestinal, KPNC Kaiser Permanente Northern California, NA not applicable.
^aCharacteristics obtained at the time of the prediagnosis CT imaging study in cases and matched controls. Mean (standard deviation) for continuous variables and N (%) for categorical variables, unless noted otherwise.
^bMatching factors.
^cAmong 518 cases and 1628 matched controls with available body mass index at the time of prediagnosis CT imaging.
^dAmong 529 cases with available at-diagnosis CT imaging.

Search