Table 2 Change in weight and tissue measurements between prediagnosis and at-diagnosis CT scans in pancreatic cancer cases

From: Adipose tissue and skeletal muscle wasting precede clinical diagnosis of pancreatic cancer

 

Prediagnosis scana

At-diagnosis scana

Absolute change between scansa

% change between scansa

% change between scans per year of follow-up

P valueb

Weight, kg

83.0 (27.1)

76.9 (22.8)

−5.2 (8.4)

−6.3 (9.6)

−4.0 (9.3)

<0.0001

Body mass index, kg/m2

28.5 (7.5)

26.5 (7.1)

−1.8 (2.8)

−6.3 (9.6)

−4.1 (9.3)

<0.0001

Visceral AT area, cm2

179.0 (188.6)

150.3 (165.6)

−20.3 (56.0)

−11.5 (33.5)

−7.1 (27.8)

<0.0001

Subcutaneous AT area, cm2

210.1 (158.1)

187.0 (137.9)

−20.9 (55.4)

−11.4 (25.0)

−6.1 (20.3)

<0.0001

Skeletal muscle area, cm2

137.7 (53.1)

128.3 (47.5)

−8.6 (16.1)

−5.9 (11.1)

−3.5 (7.0)

<0.0001

  1. AT adipose tissue, CT computed tomography.
  2. aMedian (interquartile range).
  3. bTwo-sided Wilcoxon signed-rank test.