Fig. 7: Hypothetical model for primosome assembly and DNA-unwinding coupled RNA priming of the T4 replication system. | Nature Communications

Fig. 7: Hypothetical model for primosome assembly and DNA-unwinding coupled RNA priming of the T4 replication system.

From: Structural basis of the T4 bacteriophage primosome assembly and primer synthesis

Fig. 7

a The four-step primosome assembly process is based on the four observed intermediate structures in this study. Note that the helicase loader gp59 is omitted in the scheme but is required in vivo. b A proposed four-step DNA-unwinding coupled RNA priming mechanism (steps i to iv); see text for details. Created with BioRender.com.

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