Fig. 2: Cryo-EM structures of a KRAS/BRAF/MEK1/14-3-3 complex. | Nature Communications

Fig. 2: Cryo-EM structures of a KRAS/BRAF/MEK1/14-3-3 complex.

From: Cryo-EM structure of a RAS/RAF recruitment complex

Fig. 2

a Structure of the KRAS/BRAF/MEK1/14-3-3 complex in the “RAS up” conformation. A ribbon diagram of the structure, colored as in Figure 1a, is shown together with the transparent cryo-EM density map. b Structure of the KRAS/BRAF/MEK1/14-3-3 complex in the “RAS front” conformation, determined with the BS3 cross-linked sample. A ribbon diagram of the structure, colored as in (a) above, is shown together with the transparent cryo-EM density map.

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