Fig. 5: An integrated model of schwannoma tumorigenesis and epigenetic reprogramming in response to treatment.
From: Epigenetic reprogramming shapes the cellular landscape of schwannoma
Two molecular groups of schwannoma, neural crest schwannoma and immune-enriched schwannoma, are driven by distinct mechanisms. Radiotherapy can induce immune-enriched schwannoma through metabolic and epigenetic reprogramming.
