Fig. 3: EV-sorting ability of candidate proteins in various cell sources.
From: Identification of scaffold proteins for improved endogenous engineering of extracellular vesicles
a Top ten scaffold proteins regarding intravesicular Tluc in different producer cell types. The value inside the plot refers to the percentage of intravesicular Tluc. Results are shown as mean ± standard deviation of three biological replicates. b Number of EV-sorting proteins identified for each producer cell type and overlap between cell types. c Rank of the 24 conserved EV-sorting proteins regarding intravesicular Tluc in each cell type. The value indicates the rank in each cell type as well as the average thereof. d Topology and subcellular location of the 24 conserved EV-sorting proteins. Created with BioRender.com. (e-f) Interaction network of the 24 conserved EV-sorting proteins retrieved from STRING (e) and IntAct (f) databases. Line thickness in panels (e, f) indicates the strength of data support, with thicker line standing for stronger evidence. Proteins are marked with gene names. Source data are provided as a Source Data file.
